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Igniting biotech at KAUST

KAUST ·

KAUST held its first bio-entrepreneurship ideation workshop, "Ignite Bio", for Biological and Environmental Science and Engineering students and postdoctoral fellows. Speakers from Noor Diagnostics and Discovery, Cellestia BioTech, Kyanos Biotechnology and SaudiVax shared their experiences about the startup journey. Saudi-based startups highlighted the need for services and products not currently available in the Kingdom, such as genetic diagnostic testing and local vaccine production. Why it matters: The workshop and the highlighted startups signal growing interest and opportunities for biotech innovation and entrepreneurship within Saudi Arabia.

Algae — a metabolic treasure trove

KAUST ·

KAUST researchers are exploring the potential of algae for various high-value applications, including animal feed, crop fertilizers, and waste remediation. Claudio Grunewald directs a project focused on producing high-protein algae for agriculture. Kyle Lauersen brings expertise in algal synthetic biology and metabolic engineering. Why it matters: Investment in algae research and biotechnology could yield significant returns for Saudi Arabia, contributing to sustainable solutions and economic diversification.

Algal Production Technologies workshop held at KAUST

KAUST ·

A workshop on "Scaling Algal Production Technologies for the Kingdom of Saudi Arabia" was held at KAUST from November 10-12, 2013, with attendees from government, industry, and academia. The workshop addressed algae's role in food security and its link to the food and pharmaceutical industries in Saudi Arabia. Participants reviewed the latest scientific work, the high-tech investor landscape, and mechanisms for partnerships in algal biotechnology. Why it matters: Although this event happened in 2013, it shows the early commitment of Saudi Arabia and KAUST to exploring biotechnology solutions for food security, an ongoing priority in the region.

Leading the fast-growing algae biostimulants industry

KAUST ·

KAUST, the National Livestock and Fisheries Development Program (NLFDP), and the National Research and Development Center for Sustainable Agriculture (Estidama) are collaborating to explore algae-based biostimulants for agriculture. These biostimulants, derived from marine algae, enhance plant growth and nutrient uptake without the negative impacts of chemical fertilizers. KAUST already operates a commercial-scale algae manufacturing plant capable of producing tons of algae per month for biostimulant production. Why it matters: This initiative positions Saudi Arabia as a leader in sustainable food technology by leveraging algae biostimulants to improve soil health and reduce dependence on imported raw materials.

KAUST biotechnology solution could be key to unlocking Saudi food security

KAUST ·

KAUST researchers have developed new techniques to produce nutritious microalgae in industrial volumes using seawater-adapted Spirulina and Chlorella strains. This innovation eliminates the need for freshwater, making algae-based livestock feed production sustainable and economically viable. The new Saudi Center for Algal Biotechnology Development and Aquaculture will scale up operations from a 1,000 square meter pilot plant to 42,000 square meters. Why it matters: This could help Saudi Arabia decrease its dependency on imported feed and raw food materials, aligning with its Vision 2030 goals for increased domestic food security.

KAUST and SFDA shaping the future of Saudi medical tech

KAUST ·

SFDA and KAUST jointly held a workshop to discuss AI and biotechnology in medical devices. The workshop included a leadership panel with the CEO of SFDA and the President of KAUST. SFDA emphasized the Kingdom's adoption of the National Biotechnology Strategy and its focus on improving the quality of life. Why it matters: The collaboration signals Saudi Arabia's intent to be a leader in biotechnology, leveraging AI to improve healthcare and attract investment.

Greening the scent of Arabia

KAUST ·

KAUST researchers have developed a green synthetic biology approach using engineered algae to replicate the complex fragrances of agarwood, also known as oudh. They catalogued the chemical diversity of sesquiterpenes (STPs) in 58 agarwood samples and reproduced some of the chemical complexity of agarwood STPs in algae using synthetic biology. The team used the green alga Chlamydomonas reinhardtii to produce nine distinct STP chemical products widely found in agarwood, offering a sustainable alternative to harvesting endangered trees. Why it matters: This research provides a sustainable route for producing sought-after fragrances, reducing pressure on endangered agarwood tree populations and promoting green chemistry in the region.

KAUST scientists use synthetic biology and green chemistry to synthesize popular fragrances

KAUST ·

KAUST researchers have developed a new synthetic biology process using metabolically engineered algae to produce fragrant sesquiterpenoids, the core compounds in agarwood and other perfumes. The process, developed by the Lauersen and Szekely groups, achieved yields 25 times higher than previous methods and allows for the synthesis of 103 types of fragrant sesquiterpenoids. It also incorporates an energy-efficient nanofiltration step and operates at room temperature with minimal waste. Why it matters: This sustainable bioprocess offers a green alternative to environmentally damaging harvesting of natural resources for the $44 billion fragrance industry, with potential applications in drug development.