KAUST researchers have developed a green synthetic biology approach using engineered algae to replicate the complex fragrances of agarwood, also known as oudh. They catalogued the chemical diversity of sesquiterpenes (STPs) in 58 agarwood samples and reproduced some of the chemical complexity of agarwood STPs in algae using synthetic biology. The team used the green alga Chlamydomonas reinhardtii to produce nine distinct STP chemical products widely found in agarwood, offering a sustainable alternative to harvesting endangered trees. Why it matters: This research provides a sustainable route for producing sought-after fragrances, reducing pressure on endangered agarwood tree populations and promoting green chemistry in the region.
KAUST researchers have developed a new synthetic biology process using metabolically engineered algae to produce fragrant sesquiterpenoids, the core compounds in agarwood and other perfumes. The process, developed by the Lauersen and Szekely groups, achieved yields 25 times higher than previous methods and allows for the synthesis of 103 types of fragrant sesquiterpenoids. It also incorporates an energy-efficient nanofiltration step and operates at room temperature with minimal waste. Why it matters: This sustainable bioprocess offers a green alternative to environmentally damaging harvesting of natural resources for the $44 billion fragrance industry, with potential applications in drug development.
KAUST researchers are contributing new information about desert and mangrove plants to support Saudi Arabia's Green Initiative. They are creating a soil atlas for Saudi Arabia, studying soil profiles and microbial populations in hyperarid regions. The team has also compiled the world’s largest biobank of desert microbes, sequencing each microbe's genome. Why it matters: This research is crucial for ensuring the success and sustainability of large-scale greening efforts in arid environments like Saudi Arabia.
KAUST researchers are working on green hydrogen production, which uses renewable energy to split water into hydrogen and oxygen. The current methods are capital intensive and require desalinated water, which is scarce in desert regions. KAUST is partnering with NEOM, a futuristic region on the Red Sea, where green hydrogen will be an important part of the economy. Why it matters: Innovations in green hydrogen production and cost reduction will be critical for sustainable energy in regions like Saudi Arabia.
KAUST and the Saudi Food and Drug Authority (SFDA) have partnered to develop a new method using nuclear magnetic resonance (NMR) to detect adulterants in olive oil. The method aims to identify and quantify vegetable oils mixed with olive oil, addressing concerns about the mislabeling of olive oil in the Saudi market. KAUST's comprehensive suite of NMR machines was critical for the project. Why it matters: This collaboration enhances food safety and quality control in Saudi Arabia, a major olive oil importer, and helps to ensure consumers receive authentic, high-quality products.