MBZUAI's Professor Le Song is developing an AI-driven simulation to model the human body at societal, organ, tissue, cellular, and molecular levels. The goal is to reduce the time and cost associated with bringing new medicines to market by removing the need for wet lab biological research. Song aims to create a comprehensive model using machine learning. Why it matters: This research could revolutionize drug discovery in the region by accelerating the development process and reducing reliance on traditional research methods.
Fudan University's Zhongyu Wei presented research on social simulation driven by LLMs, covering individual and large-scale social movement simulation. Wei directs the Data Intelligence and Social Computing Lab (Fudan DISC) and has published extensively on multimodal large models and social computing. His work includes the Volcano multimodal model, DISC-MedLLM, and ElectionSim. Why it matters: Using LLMs for social simulation could provide new tools for understanding and potentially predicting social dynamics in the Arab world.
A KAUST alumnus presented research on using large language models for complex disease modeling and drug discovery. LLMs were trained on insurance claims of 123 million US people to model diseases and predict genetic parameters. Protein language models were developed to discover remote homologs and functional biomolecules, while RNA language models were used for RNA structure prediction and reverse design. Why it matters: This work highlights the potential of LLMs to accelerate computational biology research and drug development, with a KAUST connection.
A KAUST research team is using cellphone mobility data, Google searches, and social media to model and predict COVID-19 spread. The models aim to forecast cases in the coming weeks and inform resource allocation, including hospital beds and medical staff. The team is using aggregated and anonymized data from cellphone companies to respect people's privacy. Why it matters: Integrating real-time digital data with epidemiological modeling can improve the speed and effectiveness of public health responses in the region and globally.
KAUST researchers have been selected as finalists for two ACM Gordon Bell Prizes for high-performance computing. One project used NVIDIA GPUs to enhance genetic studies from the UK Biobank, achieving 133x speedup over existing software. The other developed an exascale climate emulator with higher spatial-temporal resolution than current models, demonstrated on supercomputers like Shaheen III. Why it matters: The recognition highlights KAUST's strength in high-performance computing research and its contributions to both genetic analysis and climate modeling.
This paper introduces a Regulatory Knowledge Graph (RKG) for the Abu Dhabi Global Market (ADGM) regulations, constructed using language models and graph technologies. A portion of the regulations was manually tagged to train BERT-based models, which were then applied to the rest of the corpus. The resulting knowledge graph, stored in Neo4j, and code are open-sourced on GitHub to promote advancements in compliance automation.
This paper introduces Diffusion-BBO, a new online black-box optimization (BBO) framework that uses a conditional diffusion model as an inverse surrogate model. The framework employs an Uncertainty-aware Exploration (UaE) acquisition function to propose scores in the objective space for conditional sampling. The approach is shown theoretically to achieve a near-optimal solution and empirically outperforms existing online BBO baselines across 6 scientific discovery tasks.
KAUST Discovery Professor Jesper Tegnér collaborated with UK researchers to develop algorithms explaining decision-making in insects and rats. Assoc. Prof. Robert Hoehndorf's lab introduced a tool for identifying genetic variants linked to rare diseases based on patient symptoms. KAUST scientists also studied monkeypox infection of human skin using stem cells and marine microbiome adaptation to thermal changes. Why it matters: These diverse research projects highlight KAUST's contributions to computational biology, virology, and marine science, advancing knowledge with implications for healthcare and environmental challenges.