KAUST alumnus Eduardo Gorron (M.S. '12) was recruited to KAUST in 2010 as part of its second cohort of students. After graduating, he worked at SABIC on microalgae and brine from seawater, later teaching in Colombia. Currently, Gorron is completing a Ph.D. at the University of Queensland, focusing on synthetic biology to produce recombinant collagen for accelerating wound healing. Why it matters: This highlights KAUST's role in fostering international scientific talent and contributing to advancements in biotechnology and healthcare.
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Khaled Alsayegh at the King Abdullah International Medical Research Center is creating a Saudi Stem Cell Donor Registry, with 80,000 potential donors identified. The aim is to identify universal donors, reprogram their cells into induced pluripotent stem (iPS) cells, and create a gene bank for matched tissue transplants. Alsayegh is collaborating with Jesper Tegnér at KAUST to create pacemaker cells using single-cell RNA sequencing. Why it matters: This initiative could revolutionize precision medicine in KSA by providing readily available, matched cells for transplants, reducing the need for patient-specific reprogramming and improving treatment outcomes.
A smart bandage developed at KAUST aims to accelerate the healing of chronic wounds. The bandage contains sensors and drug-delivery components for real-time monitoring and treatment. Why it matters: This technology could improve patient outcomes and reduce healthcare costs associated with chronic wound management in Saudi Arabia and beyond.
Juan Carlos Izpisua Belmonte from the Salk Institute discussed aging and regenerative medicine at the KAUST 2019 Winter Enrichment Program. His team is combining gene editing and stem cell technologies to grow rat organs in mice and human cells in pig and cattle embryos. The Salk team is collaborating with KAUST to rejuvenate organs using noncoding RNAs and small metabolites. Why it matters: This research collaboration between KAUST and the Salk Institute explores innovative approaches to address age-related diseases and organ regeneration, with potential long-term impacts on healthcare in the region.
Dr. Charlotte Hauser, a bioscience professor at KAUST, has been elected as a Fellow of the National Academy of Inventors (NAI). The NAI recognized Hauser for her innovations impacting quality of life and economic development. Hauser's research focuses on smart nanomaterials for biomedical and environmental applications, including peptide-based nanostructures and 3-D bioprinting. Why it matters: This recognition highlights KAUST's contributions to innovative research in biomedicine and nanotechnology, potentially fostering further advancements in these fields within the region.
KAUST researchers are using 3D printing with a novel calcium carbonate ink to create coral support structures that accelerate coral restoration. Their approach, named 3D CoraPrint, involves printing coral microfragments onto the structure, offering a head start for reef recovery. Two methods were developed: printing a mold for reproduction and direct printing for customization. Why it matters: This eco-friendly technique provides a potentially scalable solution to combat coral reef degradation, leveraging advanced materials and fabrication for ecological conservation in the region and beyond.
KAUST's Laboratory of Stem Cells and Diseases, led by Assistant Professor Antonio Adamo, uses induced pluripotent stem cells (iPSCs) to model diseases like diabetes. The lab employs a reprogramming technique to revert patient fibroblasts into iPSCs, enabling the study of disease progression in vitro. Adamo's research focuses on enzymes and disregulated transcriptional/epigenetic mechanisms to understand disease onset. Why it matters: This research contributes to regenerative medicine and offers insights into metabolic diseases relevant to the GCC region.