MBZUAI researchers presented a study at ICML 2024 examining how data aggregation distorts causal discovery. The study argues that current methods are misled because real-world interactions happen at a micro level while observations are aggregated. Using the example of ice cream sales and temperature, they highlight how aggregation introduces "instantaneous causality" where time-lags exist. Why it matters: The research identifies a fundamental limitation in current causal discovery methods, potentially impacting disciplines relying on accurate causal inference from observational data.
MBZUAI's Kun Zhang is applying causal machine learning to improve drug development and precision medicine, focusing on answering 'why' questions. Traditional drug development is costly (est. $2B) due to extensive studies needed to determine drug toxicity and efficacy. Zhang is combining causal ML with organs-on-chips technology to improve pre-clinical drug testing, aiming to reduce the failure rate of drugs in human trials. Why it matters: By improving the accuracy of pre-clinical drug testing, this research could significantly reduce the cost and time required to bring new medicines to market in the region and worldwide.
KAUST researchers developed a new algorithm for detecting cause and effect in large datasets. The algorithm aims to find underlying models that generate data, helping uncover cause-and-effect dynamics. It could aid researchers across fields like cell biology and genetics by answering questions that typical machine learning cannot. Why it matters: This advancement could equip current machine learning methods with abilities to better deal with abstraction, inference, and concepts such as cause and effect.
MBZUAI Professor Kun Zhang's research focuses on causality in AI systems, aiming to understand underlying processes beyond data correlation. He emphasizes the importance of causality and graphical representations to model why systems produce observations and account for uncertainty. Zhang served as a program chair at the 38th Conference on Uncertainty in Artificial Intelligence (UAI) in Eindhoven. Why it matters: This highlights the growing importance of causality and uncertainty in AI research, crucial for responsible AI deployment and decision-making in the region.
MBZUAI hosted a talk on causal AI, featuring Professor Jin Tian from Iowa State University. The talk covered enriching AI systems with causal reasoning capabilities, moving AI beyond prediction to understanding. Professor Tian shared research on causal inference and estimating causal effects from data, using a novel estimator with double/debiased machine learning (DML) properties. Why it matters: Causal AI can improve the explainability, robustness, and adaptability of AI systems, addressing limitations of purely statistical models.
A new framework for constructing confidence sets for causal orderings within structural equation models (SEMs) is presented. It leverages a residual bootstrap procedure to test the goodness-of-fit of causal orderings, quantifying uncertainty in causal discovery. The method is computationally efficient and suitable for medium-sized problems while maintaining theoretical guarantees as the number of variables increases. Why it matters: This offers a new dimension of uncertainty quantification that enhances the robustness and reliability of causal inference in complex systems, but there is no indication of connection to the Middle East.
Saber Salehkaleybar from EPFL presented a talk on causal discovery, focusing on learning causal relationships from observational data and through interventions. He discussed an approximation algorithm for experiment design under budget constraints, with applications in gene-regulatory networks. The talk also covered improvements to reduce the computational complexity of experiment design algorithms. Why it matters: Causal AI systems can lead to more intelligent decision-making in various fields.
MBZUAI researchers introduced CausalVerse, a new benchmark for causal representation learning (CRL) presented at NeurIPS 2025. CausalVerse combines high-fidelity visual complexity with access to underlying causal variables and graphs, featuring 200,000 images and 300 million video frames across 24 sub-scenes in four domains. It aims to provide a realistic and precise testbed to evaluate whether CRL methods can truly learn the right causes. Why it matters: By bridging the gap between toy datasets and real-world data, CausalVerse can drive advances in AI systems capable of understanding causality in complex scenarios.