Dr. Paolo Sassone-Corsi from UC Irvine spoke at KAUST's 2019 Winter Enrichment Program about circadian rhythms. He discussed how modern lifestyles disrupt our internal clocks, impacting our health and metabolism. Studies show that the timing of food intake affects weight gain, with eating late at night causing metabolic stress. Why it matters: This highlights the importance of circadian rhythm research for understanding and mitigating the health consequences of modern lifestyles in the region.
Nobel laureate Dr. Michael Young from Rockefeller University presented his research on circadian rhythms at KAUST as part of the 2019 Winter Enrichment Program. His work on Drosophila genes has significantly advanced the understanding of circadian rhythm mechanisms. Young's research identified nine genes that regulate circadian rhythmicity at the molecular level, influencing thousands of gene expression patterns. Why it matters: This highlights KAUST's role in hosting leading international researchers and fostering scientific exchange on fundamental biological processes.
KAUST's Winter Enrichment Program (WEP) is scheduled from January 13-24, featuring the theme of "TIME." The festival includes 12 keynote lectures from international experts, including a Nobel laureate, and explores topics like biological clocks, sleep, aging, and the universe. The program also offers workshops, exhibitions, and virtual reality experiences. Why it matters: Such science festivals can boost STEM engagement and knowledge dissemination within Saudi Arabia and internationally, aligning with KAUST's mission to promote scientific advancement.
Juan Carlos Izpisua Belmonte from the Salk Institute discussed aging and regenerative medicine at the KAUST 2019 Winter Enrichment Program. His team is combining gene editing and stem cell technologies to grow rat organs in mice and human cells in pig and cattle embryos. The Salk team is collaborating with KAUST to rejuvenate organs using noncoding RNAs and small metabolites. Why it matters: This research collaboration between KAUST and the Salk Institute explores innovative approaches to address age-related diseases and organ regeneration, with potential long-term impacts on healthcare in the region.
KAUST researchers are exploring the link between nutrition and brain-energy metabolism to address cognitive decline, dementia, and Alzheimer’s disease. Dr. Pierre Magistretti and Dr. Johannes le Coutre are collaborating on ways to merge brain-energy metabolism research into the field of nutrition. They published an article entitled “Goals in Nutrition Science 2015-2020” in the journal Frontiers in Nutrition. Why it matters: This research could lead to nutritional interventions to hinder or prevent cognitive decline, offering a new approach beyond traditional drug treatments.