KAUST researchers led by Dr. Niveen Khashab have developed thermosensitive liposomes for controlled drug release, particularly in cancer therapies. The liposomes are designed to release drugs only when they reach heated tumor tissue, minimizing systemic side effects. Cholesterol moieties are used as anchors to create a "nail" or "comb" effect, enabling temperature-triggered drug release inside cells. Why it matters: This targeted drug delivery system could significantly improve the efficacy and reduce the toxicity of cancer treatments.
KAUST Research Scientist Dr. Ram Karan received a Young Scientist Award at the 15th International Congress on Thermophiles in Japan for his work on extremozymes from Red Sea brine pools. His research focuses on identifying, purifying, and bioengineering microbial proteins from these pools. He utilizes single-amplified genomes (SAGs) to produce extremozyme proteins without needing to grow cells in the lab. Why it matters: This award recognizes KAUST's innovative research into extremophiles, which have the potential to develop novel, sustainable biotechnical processes for industrial applications.
Dr. Fernando Albarracin from the Technology Innovation Institute has presented a novel microwave applicator design for hyperthermia, potentially useful in cancer treatment. The design combines two flat dielectric graded-index (GRIN) lenses to localize electromagnetic energy within a specific spot in the tissue. This system offers a suitable alternative to conventional antenna-based applicators by considering the interface between free space and human tissue. Why it matters: This research introduces a new approach to hyperthermia treatment that could improve the precision and effectiveness of cancer therapy in the region.
KAUST is spearheading geothermal energy research in Saudi Arabia to support the Kingdom's Vision 2030 goals. In early 2024, KAUST and TAQA Geothermal partnered to drill a 400-meter test well on the KAUST campus for subsurface data collection. KAUST aims to serve as a testbed for geothermal technology development and deployment across the country. Why it matters: Geothermal energy offers a consistent, weather-independent renewable energy source that could significantly reduce emissions and boost economic efficiency in Saudi Arabia.
IBM and MBZUAI have partnered to create an AI Center of Excellence, with the goal of driving sustainability in the region. The center will use AI to monitor, model, and visualize climate change, providing decision-makers with data to address issues like the urban heat island effect. Dr. Fahad Khan, Dr. Salman Khan, and Dr. Levente Klein from MBZUAI are leading the research. Why it matters: This collaboration highlights the UAE's commitment to using AI to tackle critical climate challenges and supports the upcoming COP28 in Dubai.
Malaria No More, the Crown Prince Court of Abu Dhabi, and the Reaching the Last Mile program launched the Institute for Malaria and Climate Solutions (IMACS) to combat malaria amidst climate change. Mohamed Bin Zayed University for Artificial Intelligence (MBZUAI) joined as a technical partner, providing research support leveraging AI and data science. The initiative aims to develop and implement AI-driven strategies to address the impact of climate change on malaria transmission. Why it matters: This partnership highlights the UAE's commitment to using AI for global health challenges, particularly in combating climate-sensitive diseases like malaria.
KAUST researchers have developed a passive cooling system that uses solar energy to evaporate water and regenerate salt for reuse, achieving temperatures as low as 3.6 degrees Celsius. The system uses ammonium nitrate (NH4NO3) due to its high solubility and low cost. The crystallized salt stores solar energy and can be reused for cooling when needed. Why it matters: This off-grid design offers a sustainable and inexpensive cooling solution for communities in hot regions with limited electricity access, addressing a critical need exacerbated by climate change.
A KAUST-led team developed a superabsorbent polyacrylate film for passive cooling, combining radiative and evaporative techniques without extra energy. The film uses sodium polyacrylate to absorb moisture and form a reflective film, reducing solar heating. Experiments showed the film lowered temperatures by five degrees Celsius, with simulations indicating a 3.3 percent reduction in total energy consumption. Why it matters: This innovation offers a sustainable alternative to traditional cooling systems, reducing carbon emissions and strain on energy grids in hot climates.