Janet Kelso from the Max Planck Institute and Sudhir Kumar from Temple University discussed evolutionary biology in a KAUST Facebook Live interview. Kelso's research focuses on interactions between modern humans and Neanderthals, finding similarities in DNA and benefits for environmental adaptation. Kumar's work, highly cited, involves big data analyses in evolutionary biology. Why it matters: The interview highlights KAUST's engagement with international experts in bioinformatics and evolutionary biology, promoting interdisciplinary research and knowledge dissemination.
Shozo Yokoyama, a biology professor at Emory University specializing in color vision evolution, was interviewed by KAUST. Yokoyama's lab identified amino acids regulating red-green and UV vision in vertebrates. He emphasizes the importance of young scientists developing fresh perspectives on evolution and learning directly from animals. Why it matters: While not directly an AI story, the piece highlights KAUST's broader research focus and its investment in attracting and showcasing international scientific expertise, relevant to building a strong research ecosystem.
KAUST's Computational Bioscience Research Center (CBRC) held a Research Conference on Big Data Analyses in Evolutionary Biology. The conference focused on the impact of large "omics" datasets on evolutionary biology, requiring big data approaches for analysis. Researchers discussed how computer science can contribute to biology and vice versa. Why it matters: Such interdisciplinary events at KAUST can foster innovation at the intersection of computational science and biology, advancing research in both fields.
Dr. Takashi Gojobori, a KAUST professor and expert in molecular evolution, received an honorary doctoral degree from National Cheng Kung University (NCKU) in Taiwan. The degree recognizes Gojobori's contributions to evolutionary genomics and molecular evolution. A KAUST delegation led by VP James A. Calvin attended the conferring ceremony. Why it matters: The recognition highlights KAUST's faculty quality and contributions to international research collaborations.
NYU Professor Michael Purugganan presented at KAUST's 2014 Winter Enrichment Program (WEP 2014) on the origins of crop species. He discussed how genome sequencing is improving our understanding of crop evolution, using date fruits collected in Jeddah as an example. His research on rice showed that two varieties, japonica and indica, share a single common ancestor, contrary to previous assumptions. Why it matters: Understanding crop evolution can help adapt crops to changing environments, which is crucial for food security in regions like the Middle East.
KAUST researchers developed a statistical approach to improve the identification of cancer-related protein mutations by reducing false positives. The method uses Bayesian statistics to analyze protein domain data from tumor samples, accounting for potential errors due to limited data. The team tested their method on prostate cancer data, successfully identifying a known cancer-linked mutation in the DNA binding protein cd00083. Why it matters: This enhances the reliability of cancer research at the molecular level, potentially accelerating the discovery of new therapeutic targets.
Juan Carlos Izpisua Belmonte from the Salk Institute discussed aging and regenerative medicine at the KAUST 2019 Winter Enrichment Program. His team is combining gene editing and stem cell technologies to grow rat organs in mice and human cells in pig and cattle embryos. The Salk team is collaborating with KAUST to rejuvenate organs using noncoding RNAs and small metabolites. Why it matters: This research collaboration between KAUST and the Salk Institute explores innovative approaches to address age-related diseases and organ regeneration, with potential long-term impacts on healthcare in the region.
KAUST researchers have identified a protein complex of HuR and YB1 that stabilizes messenger RNA during muscle-fiber formation. The complex protects RNA as it carries muscle-forming code through the cell. Further research aims to elucidate the individual roles of each protein in the stabilization process. Why it matters: Understanding this RNA-stabilizing complex could lead to new therapies for muscle recovery and the prevention of muscle-related pathologies.