KAUST researchers are exploring the link between nutrition and brain-energy metabolism to address cognitive decline, dementia, and Alzheimer’s disease. Dr. Pierre Magistretti and Dr. Johannes le Coutre are collaborating on ways to merge brain-energy metabolism research into the field of nutrition. They published an article entitled “Goals in Nutrition Science 2015-2020” in the journal Frontiers in Nutrition. Why it matters: This research could lead to nutritional interventions to hinder or prevent cognitive decline, offering a new approach beyond traditional drug treatments.
KAUST researchers have identified a protein complex of HuR and YB1 that stabilizes messenger RNA during muscle-fiber formation. The complex protects RNA as it carries muscle-forming code through the cell. Further research aims to elucidate the individual roles of each protein in the stabilization process. Why it matters: Understanding this RNA-stabilizing complex could lead to new therapies for muscle recovery and the prevention of muscle-related pathologies.
KAUST researchers discovered that the red algae strain Galdieria yellowstonesis can convert sugars from chocolate-processing waste into C-phycocyanin, a valuable blue pigment. The study found that high levels of carbon dioxide promote Galdieria growth, and the resulting phycocyanin was deemed food-safe by the U.S. FDA. Mars supported the research by providing chocolate samples. Why it matters: This research offers a sustainable method for waste management and contributes to a circular economy in the region, with potential applications in food, cosmetics, and pharmaceuticals.
KAUST researcher Corrado Calì won an award at the Brainstorming Research Assembly for Young Neuroscientists (BraYn) in Italy for his work on glycogen modulation and synapse stabilization. Calì presented research in collaboration with KAUST Professor Andrea Falqui and Dr. Elena Vezzoli from the University of Milan, investigating the lactate shuttle's involvement in synaptic plasticity. Calì and KAUST colleagues are also collaborating with the Blue Brain Project to produce a computer simulation of astrocyte-neuron coupling, using 3D virtual reality to investigate brain cell morphologies at the nanoscale. Why it matters: This award recognizes KAUST's contribution to neuroscience research and highlights the university's collaborative efforts in understanding brain plasticity and developing advanced tools for studying brain structures.
KAUST researchers have discovered how sea anemones recycle nitrogen waste, allowing them to thrive in nutrient-poor ocean environments. The study used laser microdissection and single-cell RNA-sequencing to analyze tissue-specific gene expression in Aiptasia. They found that anemones distribute glucose received from symbionts across tissues to recycle nitrogen waste. Why it matters: This research enhances understanding of coral reef ecosystems and their resilience, which is particularly relevant for Red Sea biodiversity and Saudi Arabia's environmental efforts.
KAUST researchers have developed a surface treatment for jute storage bags to prevent moisture-induced damage to stored grains. The treatment involves roughening the jute surface with an alkali and applying a thin layer of paraffin wax. Experiments showed that seed moisture content reduced by up to 7.5 percent in wax-coated bags, and seed germination efficacy after storage was up to 35 percent higher. Why it matters: This simple, scalable technique could significantly reduce grain losses in developing countries and provide an environmentally friendly alternative for grain storage.
Researchers at KAUST, USTC, and SUSTech have developed a method for carbon capture and storage using guanidinium sulfate salt to create clathrate structures that trap CO2 molecules. This salt-based structure mimics methane hydrate activity and captures CO2 through physisorption, without water or nitrogen interference. The method allows CO2 to be carried as a solid powder at ambient temperature and pressure, offering a less energy-intensive alternative to traditional methods. Why it matters: This innovation introduces a new, energy-efficient way to store and transport CO2 as a solid, potentially revolutionizing carbon capture and storage technologies in the region and beyond.