KAUST and Janssen Pharmaceutical (Johnson & Johnson) are collaborating to research and innovate in neglected tropical diseases, focusing on dengue fever. They signed an MoU to establish a dengue fever research program and an infectious disease R&D center at KAUST's National BioPark. The partnership marks Johnson & Johnson's first university collaboration in Saudi Arabia. Why it matters: This collaboration signifies a major step in localizing disease research within Saudi Arabia and leveraging KAUST's AI, genomics, and data simulation expertise to address global health challenges.
MBZUAI is developing AI-powered applications to help reduce malaria's impact in Indonesia, supported by Sheikh Mohamed bin Zayed Al Nahyan's Reaching the Last Mile initiative. The applications use sensory data fusion to create "digital twins" for precise weather forecasting and real-time environmental representation. AI and clustering analysis identify recurring features contributing to malaria outbreaks, enabling preventative measures and early treatment. Why it matters: This project demonstrates AI's potential in combating climate-sensitive diseases and improving public health in vulnerable regions.
Professor Arnab Pain's group at KAUST discovered new insights on how a malaria protein enables parasites to spread malaria in human cells. Professor Haavard Rue's group upgraded the Integrated and Nested Laplace Approximation (INLA) for faster real-time modeling of large datasets. A KAUST-led study examined the stability of Y-series nonfullerene acceptors for organic solar cells. Why it matters: KAUST continues producing impactful research across diverse fields from medicine to climate change, advancing scientific knowledge and potential applications.
Malaria No More, the Crown Prince Court of Abu Dhabi, and the Reaching the Last Mile program launched the Institute for Malaria and Climate Solutions (IMACS) to combat malaria amidst climate change. Mohamed Bin Zayed University for Artificial Intelligence (MBZUAI) joined as a technical partner, providing research support leveraging AI and data science. The initiative aims to develop and implement AI-driven strategies to address the impact of climate change on malaria transmission. Why it matters: This partnership highlights the UAE's commitment to using AI for global health challenges, particularly in combating climate-sensitive diseases like malaria.
KAUST researchers have developed a CRISPR-Cas system using a heat-stable Cas13 protein (TccCas13a) from Thermoclostridium caenicola, compatible with RT-LAMP for rapid viral detection. The new assay, named OPTIMA-dx, enhances the specificity of RT-LAMP tests by reducing false positives in SARS-CoV-2 detection. The team, led by Dr. Magdy Mahfouz and doctoral student Ahmed Mahas, is transitioning the product to a startup phase for commercialization. Why it matters: This innovation could significantly improve point-of-care diagnostics for COVID-19 and other infections by providing a more accurate and easier-to-use testing method.
The KAUST Pathogen Genomics Laboratory (PGL), led by Professor Arnab Pain, is using DNA and RNA sequencing to study the SARS-CoV-2 virus. The lab is part of KAUST's Rapid Research Response Team (R3T), supporting Saudi healthcare stakeholders in combating COVID-19. Pain and his Ph.D. student Sharif Hala are partnering with the Saudi-CDC and Ministry of Health hospitals to sequence Saudi SARS-CoV-2 samples. Why it matters: This effort provides crucial data for understanding and monitoring the virus's spread and evolution within the Kingdom, informing public health strategies.
This paper examines the relationship between COVID-19 spread and weather patterns across 89 cities in Saudi Arabia using machine learning. The study uses daily COVID-19 case reports from the Saudi Ministry of Health and historical weather data. The results indicate that temperature and wind speed have the strongest correlation with the spread of COVID-19, with a random forest model achieving the best performance.
A KAUST research team is using cellphone mobility data, Google searches, and social media to model and predict COVID-19 spread. The models aim to forecast cases in the coming weeks and inform resource allocation, including hospital beds and medical staff. The team is using aggregated and anonymized data from cellphone companies to respect people's privacy. Why it matters: Integrating real-time digital data with epidemiological modeling can improve the speed and effectiveness of public health responses in the region and globally.