NYU Professor Michael Purugganan presented at KAUST's 2014 Winter Enrichment Program (WEP 2014) on the origins of crop species. He discussed how genome sequencing is improving our understanding of crop evolution, using date fruits collected in Jeddah as an example. His research on rice showed that two varieties, japonica and indica, share a single common ancestor, contrary to previous assumptions. Why it matters: Understanding crop evolution can help adapt crops to changing environments, which is crucial for food security in regions like the Middle East.
KAUST researchers have developed a genomic resource for Tausch’s goatgrass (Aegilops tauschii), a wild relative of wheat, by creating 46 high-quality genome assemblies. They compiled 493 genetically distinct accessions from an initial 900, collaborating with the Open Wild Wheat Consortium to select accessions with traits of interest, such as disease resistance and stress tolerance. Screening these assemblies helped identify rust resistance genes, including mapping a stem rust resistance gene to the Sr33 locus. Why it matters: This genomic resource will accelerate gene discovery in wheat, potentially improving modern wheat varieties and enhancing global food security.
Dr. John Bedbrook of DiCE Molecules LLC spoke at KAUST about the challenges of feeding a growing population with increasingly stressed arable land. He noted the increasing demand for meat in emerging economies exacerbates the problem. Bedbrook emphasized the role of genetics and hybridization in improving crop yields and quality to address food security. Why it matters: Investments in agricultural biotechnology are crucial for the GCC region to enhance food security and reduce reliance on imports amid changing climate conditions.
KAUST researchers are working to improve gene editing tools, specifically CRISPR/Cas9, for crop bioengineering to address food security challenges. Magdy Mahfouz's lab is developing a germline engineering platform to produce gene-edited plants without foreign DNA and bypass time-consuming tissue culture. A recent European court decision classifies CRISPR/Cas9 crops as GMOs, facing stringent regulations, contrasting with the U.S. where CRISPR-edited mushrooms are already available. Why it matters: Advances in gene editing at KAUST could significantly enhance crop yields and stress tolerance in the region, but regulatory hurdles remain a key challenge for deployment.
KAUST plant scientists are advocating for the deployment of new plant breeding technologies, including gene editing, to enhance global food security. Researchers Mark Tester and Magdy Mahfouz highlight these methods' potential to improve crops by minimizing crop life cycle for research on breeding, selection, and fixing of useful genes. They argue these technologies offer alternatives to genetically modified crops, potentially lowering regulatory costs and increasing seed affordability for farmers in developing countries. Why it matters: These advancements, coupled with regional seed-sharing initiatives, could significantly boost food production and accessibility in less-developed countries in the Middle East and globally.
KAUST Professor Salim Al-Babili is working to improve crop performance and nutritional value, with a focus on pearl millet. He received a $5 million grant from the Gates Foundation in 2018 to combat the parasitic plant Striga hermonthica, which causes billions in losses annually in Sub-Saharan Africa. His team is developing hormone-based strategies to protect pearl millet from Striga infestation, a project spanning lab research to field trials in Saudi Arabia and Africa. Why it matters: This research addresses critical food security challenges in both Africa and the Middle East by developing practical tools for smallholder farmers, bridging the gap between lab discoveries and real-world applications.
Hanin Ahmed, a KAUST Ph.D. graduate in plant science, is now an Ibn-Rushd Postdoctoral Fellow at The Centre for Anthropology and Genomics of Toulouse, France. Her Ph.D. research at KAUST focused on the population genomics and evolutionary history of fonio millet and einkorn wheat. One key finding was the influence of ethnic groups on the genetic diversity of fonio millet, and insights into wheat adaptation during early agriculture from einkorn wheat research published in Nature. Why it matters: This highlights KAUST's role in training researchers who are contributing to advancements in genomics and agriculture, with implications for crop improvement and understanding the impact of social factors on plant genetics.
KAUST's Center of Excellence for Sustainable Food Security (CoE-SFS) has launched 12 translation projects focused on plant growth and water security, establishing partnerships with public and private entities to scale up research. Mark Tester's team developed stress-tolerant rootstocks, grafted onto crops like tomatoes, that thrive in hot, dry conditions with increased yields. Through his start-up Iyris, Tester is conducting commercial field trials in over 12 countries. Why it matters: These efforts to adapt agriculture to environmental change are crucial for ensuring food security in Saudi Arabia, the region, and globally, especially in the face of climate change and limited water resources.