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New smart-drug research may help target cancer therapy

KAUST · Dec 1

KAUST researchers led by Dr. Niveen Khashab have developed thermosensitive liposomes for controlled drug release, particularly in cancer therapies. The liposomes are designed to release drugs only when they reach heated tumor tissue, minimizing systemic side effects. Cholesterol moieties are used as anchors to create a "nail" or "comb" effect, enabling temperature-triggered drug release inside cells. Why it matters: This targeted drug delivery system could significantly improve the efficacy and reduce the toxicity of cancer treatments.

Fernando Albarracin, Young Scientist Award, URSI GASS 2020

TII · Mar 17

Dr. Fernando Albarracin from the Technology Innovation Institute has presented a novel microwave applicator design for hyperthermia, potentially useful in cancer treatment. The design combines two flat dielectric graded-index (GRIN) lenses to localize electromagnetic energy within a specific spot in the tissue. This system offers a suitable alternative to conventional antenna-based applicators by considering the interface between free space and human tissue. Why it matters: This research introduces a new approach to hyperthermia treatment that could improve the precision and effectiveness of cancer therapy in the region.