KAUST professors Samir Hamdan and Nina Fedoroff collaborated on research published in Nucleic Acids Research focusing on microRNA (miRNA) biogenesis in plants. The study examined miRNA production in Arabidopsis thaliana and found that the protein SERRATE (SE) is integral to the processing of pri-miRNA by DCL1. They characterized the interactions of SE with RNA and DCL1, elucidating the mechanism by which SE promotes DCL1 activity. Why it matters: Understanding miRNA biogenesis could help modify crop plants to better tolerate stressful conditions, potentially increasing crop yields and productivity in the region.
KAUST Associate Professor Liming Xiong is researching how plants adapt to drought conditions, focusing on reducing water consumption, increasing water uptake, and surviving under stress. His "whole plant" approach aims to identify major genes controlling water uptake, water loss, and cellular detoxification. The research seeks to develop plants that use water more efficiently or can be irrigated with brackish water, important for agriculture in Saudi Arabia. Why it matters: Understanding the molecular mechanisms of plant drought tolerance can help in breeding stress-tolerant crops suitable for the arid conditions in the region.
KAUST researchers collaborated to identify molecular pathways for plant biofortification of vitamin A. A KAUST group demonstrated high pressure conversion of carbon dioxide into useful products. Another team designed a biosensor using metal oxide transistors to detect glucose in saliva. Why it matters: These projects highlight KAUST's contributions to biotechnology, environmental sustainability, and healthcare through advanced materials and molecular techniques.
KAUST researchers have identified a gene, CLAMT1b, in pearl millet that affects its vulnerability to the parasitic weed Striga hermonthica. Pearl millet strains lacking CLAMT1b were found to be resistant to the weed, while those expressing the gene were susceptible. The gene's presence leads to the secretion of strigolactones, promoting interaction with Striga, but its absence does not harm symbiotic relationships with beneficial fungi. Why it matters: This discovery offers new breeding strategies to enhance pearl millet's resistance to parasitic weeds, bolstering food security in arid regions like Saudi Arabia and Africa where the crop is vital.
KAUST plant scientists are advocating for the deployment of new plant breeding technologies, including gene editing, to enhance global food security. Researchers Mark Tester and Magdy Mahfouz highlight these methods' potential to improve crops by minimizing crop life cycle for research on breeding, selection, and fixing of useful genes. They argue these technologies offer alternatives to genetically modified crops, potentially lowering regulatory costs and increasing seed affordability for farmers in developing countries. Why it matters: These advancements, coupled with regional seed-sharing initiatives, could significantly boost food production and accessibility in less-developed countries in the Middle East and globally.
KAUST researchers are contributing new information about desert and mangrove plants to support Saudi Arabia's Green Initiative. They are creating a soil atlas for Saudi Arabia, studying soil profiles and microbial populations in hyperarid regions. The team has also compiled the world’s largest biobank of desert microbes, sequencing each microbe's genome. Why it matters: This research is crucial for ensuring the success and sustainability of large-scale greening efforts in arid environments like Saudi Arabia.
KAUST researchers have developed a genomic resource for Tausch’s goatgrass (Aegilops tauschii), a wild relative of wheat, by creating 46 high-quality genome assemblies. They compiled 493 genetically distinct accessions from an initial 900, collaborating with the Open Wild Wheat Consortium to select accessions with traits of interest, such as disease resistance and stress tolerance. Screening these assemblies helped identify rust resistance genes, including mapping a stem rust resistance gene to the Sr33 locus. Why it matters: This genomic resource will accelerate gene discovery in wheat, potentially improving modern wheat varieties and enhancing global food security.
KAUST postdoctoral fellow Muhammad Jamil won the best poster award at the 15th World Congress on Parasitic Plants for his research on combating the parasitic plant *Striga hermonthica*. His poster outlined his work at KAUST on developing technologies to help farmers in sub-Saharan Africa control this weed, which severely impacts cereal crops. Jamil is part of the Bill & Melinda Gates Foundation-funded project at KAUST focused on controlling *Striga* in pearl millet. Why it matters: This recognition highlights KAUST's contributions to addressing critical food security challenges in Africa through innovative agricultural technologies.