Scientists uncover how brain support cells influence memory

Summary

Scientists at King Abdullah University of Science and Technology (KAUST) have discovered that astrocytes, a type of non-neuronal cell, actively influence communication between neurons and processes linked to learning and memory. Their study, published in The Journal of Physiology, revealed that lactate not only provides energy to neurons but also triggers a signaling pathway within them, challenging the traditional view of astrocytes as passive support cells. This research, conducted largely at KAUST with international collaboration from Italy and Switzerland, provides new insights into the molecular mechanisms supporting brain cell communication and synaptic plasticity. Why it matters: These findings are significant for understanding fundamental brain science and could open new avenues for therapeutic strategies targeting neurological disorders and memory loss.