KAUST hosted the Nature Conferences: Brain Energy Metabolism in Health and Disease, convening experts to discuss brain energy use and its impact on function and disease. Researchers from KAUST and global institutions shared insights on metabolic interactions among brain cells and the brain's role in whole-body energy regulation. KAUST's President Sir Edward Byrne emphasized brain health as essential for the cognitive economy, aligning with Saudi Arabia’s Vision 2030. Why it matters: The conference highlights KAUST's growing role in global neuroscience research and its commitment to addressing critical health challenges through international collaboration.
KAUST researchers are exploring the link between nutrition and brain-energy metabolism to address cognitive decline, dementia, and Alzheimer’s disease. Dr. Pierre Magistretti and Dr. Johannes le Coutre are collaborating on ways to merge brain-energy metabolism research into the field of nutrition. They published an article entitled “Goals in Nutrition Science 2015-2020” in the journal Frontiers in Nutrition. Why it matters: This research could lead to nutritional interventions to hinder or prevent cognitive decline, offering a new approach beyond traditional drug treatments.
KAUST's Vice President of Research, Professor Pierre Magistretti, presented the 2023 Nansen Neuroscience Lecture in Oslo. The lecture highlighted his discovery of the astrocyte-neuron lactate shuttle and its role in brain physiology and pathology. His research explains how astrocytes feed neurons lactate as a primary energy source, impacting memory and cognition. Why it matters: The lecture recognizes KAUST's contribution to neuroscience and highlights the importance of understanding brain energy consumption for treating neurological disorders.
KAUST Discovery highlights the contributions of Magistretti to the field of neuroenergetics. His research explores the cellular and molecular basis of brain energy metabolism and brain imaging. Magistretti's group discovered mechanisms underlying the coupling between neuronal activity and energy consumption, revealing the role of astrocytes. Why it matters: Understanding brain energy metabolism and the role of glial cells can advance brain imaging techniques and our understanding of neuronal processes.
KAUST Professor Pierre Magistretti received the 2016 Fondation IPSEN Neuronal Plasticity prize for his work in neuroenergetics. The award recognizes Magistretti's contributions to understanding the relationship between neuronal activity and brain energy consumption. He shares the award with Dr. David Attwell and Dr. Marcus Raichle, and will be honored at FENS in Copenhagen. Why it matters: This award highlights KAUST's contribution to international neuroscience research and strengthens its reputation in biological and environmental science.